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SC 51089
Artikelnummer: TGM-T23331-10mg
Description: SC 51089 is a selective prostaglandin receptor PGE2 antagonist with selectivity for prostaglandin receptor subtypes and antinociceptive activity that improves motor deficits and rescues memory decline in the Huntington's disease R6/1 mouse model . Target: Prostaglandin Receptor. Smiles:...
| Schlagworte: | SC 51089 free base |
| Anwendung: | EP1 antagonist |
| CAS | 146033-02-5 |
| MW: | 459.33 D |
ab 292,00 €
Abetimus
Artikelnummer: TGM-T83217-50mg
Description: Abetimus (LJP 394 free base), an immunosuppressant composed of four double-stranded DNA (dsDNA) oligonucleotides, can crosslink anti-dsDNA antibodies on B cell surfaces and reduce anti-dsDNA antibody levels, offering research potential for systemic lupus erythematosus [1]. Target: Others. Smiles:...
| Schlagworte: | LJP 394 free base |
| CAS | 167362-48-3 |
| MW: | 318.28 D |
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Semapimod
Artikelnummer: TGM-T79304-100mg
Description: Semapimod is an inhibitor of proinflammatory cytokine production, capable of suppressing TNF-alpha, IL-1beta, and IL-6. It hinders TLR4 signaling with an IC50 of approximately 0.3 µM, impedes p38 MAPK, and reduces nitric oxide production in macrophages. This compound shows promise for treating various...
| Schlagworte: | CPSI-2364, CNI-1493 free base |
| CAS | 352513-83-8 |
| MW: | 744.9 D |
ab 1.520,00 €
Imiquimod 2HCl
Artikelnummer: TGM-T0134L-10mg
Description: Imiquimod 2HCl is a toll-like receptor 7 (TLR7) agonist and an immunomodulator with antiviral and antitumor activity.Imiquimod 2HCl can be used to construct a psoriasis-like mouse model, which can be used to study periocular skin cancers, pemphigus foliaceus, and COVID-19 infection. Target: TLR,...
| Schlagworte: | Imiquimod 2HCl(99011-02-6 Free base) |
| CAS | 2995277-02-4 |
| MW: | 313.23 D |
ab 194,00 €
Lasalocid A ammonium
Artikelnummer: TGM-T15717L-5mg
Description: Lasalocid A ammonium is an amine-selective ion carrier and feed additive with antimicrobial activity and antibiotic, growth-promoting properties, inhibits the protozoa of falciparum malaria, and can be used in the study of microbial infections. Target: Parasite, Antibacterial, Antibiotic. Smiles:...
| Schlagworte: | Lasalocid A ammonium(25999-31-9 Free base) |
| MW: | 607.82 D |
ab 194,00 €
ZIP (SCRAMBLED) Acetate
Artikelnummer: TGM-T22175L-10mg
Description: ZIP (SCRAMBLED) Acetate (ZIP (SCRAMBLED) Acetate (908012-18-0 Free Base)) is a scrambled peptide that can be used as a negative control for zeta inhibitory peptide (ZIP). Target: Others. Smiles:...
| Schlagworte: | ZIP (SCRAMBLED) Acetate(908012-18-0 Free Base) |
| MW: | 1988.43 D |
ab 67,00 €
Spadin Acetate
Artikelnummer: TGM-T22178L-10mg
Description: Spadin Acetate is a natural peptide derived from a propeptide released in blood. Spadin Acetate is able to block the TREK-1 channel activity. Spadin Acetate binds specifically to TREK-1 with an affinity of 10 nM. Target: Others. Smiles:...
| Schlagworte: | Spadin Acetate(1270083-24-3 Free base) |
| MW: | 2072.37 D |
ab 98,00 €
(R)-3,4-DCPG HCl
Artikelnummer: TGM-T23215L-10mg
Description: (R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord. Target: GluR. Smiles: OC(C1=C(C(O)=O)C=CC([C@H](C(O)=O)N)=C1)=O.[H]Cl. References: Moldrich RX, et al. Anticonvulsant activity...
| Schlagworte: | (R)-3,4-DCPG HCl(201730-10-1 Free base) |
| MW: | 275.64 D |
ab 194,00 €
SDZ 220-040 ammonium
Artikelnummer: TGM-T23344L-10mg
Description: SDZ 220-040 ammonium is a competitive glutamate ionotropic receptor NMDA antagonist used in the study of neurological disorders. Target: NMDAR. Smiles: ClC1=C(C=CC(Cl)=C1)C2=CC(C[C@H](N)C(O)=O)=C(C(CP(O)([O-])=O)=C2)O.[NH4+]. References: Brian G Forde. et al. Glutamate signalling via a MEKK1...
| Schlagworte: | SDZ 220-040 ammonium (174575-40-7 Free base) |
| MW: | 437.21 D |
ab 259,00 €
Amicoumacin A FA
Artikelnummer: TGM-T23725L-5mg
Description: Amicoumacin A FA has antimicrobial activity, inhibiting S. purpureus and S. aureus, and can be used in the study of microbial infections. Target: Antibacterial. Smiles: O=C1C2=C(O)C=CC=C2C[C@@](O1)([H])[C@H](CC(C)C)NC([C@@H](O)[C@@H](O)[C@@H](N)CC(N)=O)=O.[H]C(O)=O. References: Simon Cutting,et...
| Schlagworte: | Amicoumacin A FA(78654-44-1 Free base) |
| MW: | 469.49 D |
ab 194,00 €
BMY 25368 HCl
Artikelnummer: TGM-T23811L-5mg
Description: BMY 25368 HCl is a competitive histamine H2 receptor antagonist that antagonizes gastric secretion stimulated by pentagastrin, ethacrynic choline, and food. Target: Histamine Receptor. Smiles: Cl.O=C1C(=O)C(NCCCOC2=CC=CC(=C2)CN3CCCCC3)=C1N. References: Orsini JA,et al. Effects of a histamine type-2...
| Schlagworte: | BMY 25368 HCl(86134-80-7 Free base) |
| CAS | 86134-36-3 |
| MW: | 379.88 D |
ab 88,00 €
Isatoribine
Artikelnummer: TGM-T24178-5mg
Description: Isatoribine(ANA245) free base is a potent TLR7 receptor agonist with anti-hepatitis C virus infection activity for the study of HCV infection. Target: TLR, HCV Protease. Smiles: O=C1N(C2=C(S1)C(=O)N=C(N)N2)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O. References: Horsmans Y, et al. Isatoribine, an agonist of...
| Schlagworte: | Isatoribine, ANA-245, Immusine, ANA245, Isatoribine monohydrate, Isatoribine free base, ANA 245 |
| CAS | 122970-40-5 |
| MW: | 316.29 D |
ab 257,00 €