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Cot inhibitor-1 hydrochloride
Cot inhibitor-1 hydrochloride

Artikelnummer: TGM-T10865L-10mg

Description: Cot inhibitor-1 hydrochloride is an inhibitor of tumor progression loci-2 kinase (IC50 = 28 nM) and inhibits the production of TNF-alpha in human whole blood (IC50 = 5.7 nM). Target: TNF, MAPK. Smiles: N#CC1=CN=C2C(Cl)=CC(NCC3=CN(CCN4CCCCCC4)N=N3)=CC2=C1NC5=CC=C(C(Cl)=C5)F.Cl. References: Junjun Wu, et...
Schlagworte: Cot inhibitor-1 hydrochloride(915365-57-0 Free base)
MW: 589.92 D
ab 126,00 €
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Cysteine Protease inhibitor hydrochloride
Cysteine Protease inhibitor hydrochloride

Artikelnummer: TGM-T10925L-100mg

Description: Cysteine Protease inhibitor hydrochloride is a cysteine protease inhibitor. Target: Others. Smiles: N#CC1=NC(OC2=CC(C3=CC=C(CN)C=C3)=CC=C2)=CC=N1.Cl
Schlagworte: Cysteine Protease inhibitor hydrochloride (921625-62-9 free base)
Anwendung: Cysteine Protease inhibitor
CAS 2197053-49-7
MW: 338.79 D
ab 1.140,00 €
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Deltasonamide 2 hydrochloride
Deltasonamide 2 hydrochloride

Artikelnummer: TGM-T10994L-500mg

Description: Deltasonamide 2 hydrochloride is a competitive high-affinity PDEdelta inhibitor with a Kd of approximately 385 pM. Target: PDE. Smiles: O=S(C1=CC=C(S(=O)(N(CC2=CC=C(Cl)C=C2)C3CCCC3)=O)C=C1)(N([C@H]4CC[C@H](N)CC4)CC5=NC(NC)=NC=C5)=O.[H]Cl. References: Klein CH, et al. PDEdelta inhibition impedes the...
Schlagworte: Deltasonamide 2 hydrochloride (2088485-34-9 free base)
MW: 683.71 D
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Lurasidone metabolite 14326 hydrochloride
Lurasidone metabolite 14326 hydrochloride

Artikelnummer: TGM-T11893L-10mg

Description: Lurasidone metabolite 14326 hydrochloride, an active metabolite of the atypical antipsychotic Lurasidone, maintains its significant function in pharmacological efficacy. Target: Others. Smiles: O=C([C@]([C@@H]1C[C@H](O)[C@H]2C1)([H])[C@]2([H])C3=O)N3C[C@H]4[C@H](CN(CC5)CCN5C6=NSC7=C6C=CC=C7)CCCC4.Cl....
Schlagworte: Lurasidone metabolite 14326 hydrochloride (186204-33-1 free base)
MW: 545.14 D
ab 239,00 €
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p-Ethynylphenylalanine hydrochloride
p-Ethynylphenylalanine hydrochloride

Artikelnummer: TGM-T10142L-50mg

Description: p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent, and specific inhibitor of TPH[1]. Its potential to selectively and reversibly inhibit serotonin biosynthesis may contribute to characterizing the role of serotonin in behavioral and physiological activities[1]....
Schlagworte: 4-Ethynyl-L-phenylalanine HCL, p-Ethynylphenylalanine hydrochloride(278605-15-5 free base)
CAS 188640-63-3
MW: 225.67 D
ab 31,00 €
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ADRA1D receptor antagonist 1 HCl
ADRA1D receptor antagonist 1 HCl

Artikelnummer: TGM-T10250-1mg

Description: ADRA1D receptor antagonist 1 HCl is an orally active, potent and selective alpha1D adrenergic receptor antagonist (Ki: 1.6 nM) with potential antiproliferative activity. Target: Adrenergic Receptor. Smiles: Cl.C[C@H](c1cccc(c1)C#N)n1cc(Cl)cc(C(N)=O)c1=N. References: Sakauchi N,et al. Discovery of...
Schlagworte: ADRA1D receptor agonist 1, ADRA1D receptor antagonist 1 HCl(1191908-24-3 free base)
CAS 1191908-14-1
MW: 337.2 D
198,00 €
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Bax inhibitor peptide V5 acetate
Bax inhibitor peptide V5 acetate

Artikelnummer: TGM-T10463L-10mg

Description: Bax inhibitor peptide V5 acetate (Bax inhibitor peptide V5 acetate(579492-81-2 free base)) is a Bax-mediated apoptosis inhibitor, used for cancer treatment. Target: Apoptosis. Smiles: O=C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CC(C)C)=O)CCSC)[C@@H]1CCCN1C([C@H](C(C)C)N)=O.CC(O)=O. References: Jo MJ,...
Schlagworte: Bax inhibitor peptide V5 acetate(579492-81-2 free base)
MW: 646.85 D
ab 45,00 €
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RTI-13951-33 hydrochloride
RTI-13951-33 hydrochloride

Artikelnummer: TGM-T12778-50mg

Description: RTI-13951-33 hydrochloride is a potent, selective, and brain-penetrant GPR88 agonist, exhibiting an EC50 of 25 nM in vitro cAMP functional assay. It significantly reduces alcohol reinforcement and intake behaviors in rats [1]. Target: Others. Smiles:...
Schlagworte: RTI-13951-33 hydrochloride (2244884-08-8 free base)
MW: 532.5 D
ab 1.360,00 €
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PROTAC BRD9-binding moiety 1 hydrochloride
PROTAC BRD9-binding moiety 1 hydrochloride

Artikelnummer: TGM-T13915L-50mg

Description: PROTAC BRD9-binding moiety 1 hydrochloride inhibits BRD9 activity by binding to BRD9, utilizing the PROTAC (Proteolysis Targeting Chimera) mechanism. Target: Others. Smiles: O=C(O)COC1=CC=C(C2=CN(C)C(C3=C2SC(C(NC(CC4)CCS4(=O)=O)=N)=C3)=O)C=C1OC.Cl. References: Remillard D, et al. Degradation of the BAF...
Schlagworte: PROTAC BRD9-binding moiety 1 hydrochloride (2097512-23-5 free base)
MW: 556.05 D
ab 371,00 €
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PXS-5153A monohydrochloride
PXS-5153A monohydrochloride

Artikelnummer: TGM-T12585L-100mg

Description: PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC 50 of <40 nM for LOXL2 across all mammalian species and an IC 50 of 63 nM for human LOXL3. PXS-5153A monohydrochloride dose-dependently reduced...
Schlagworte: PXS-5153A monohydrochloride (2125956-82-1 free base)
CAS 2125956-82-1
MW: 475.41 D
ab 986,00 €
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STING agonist-3 trihydrochloride
STING agonist-3 trihydrochloride

Artikelnummer: TGM-T13014L-500mg

Description: STING agonist-3 trihydrochloride is a selective and non-nucleotide agonist of small-molecule STING(pEC50 and pEC50 of 7.5 and 9.5, respectively), has durable anti-tumor effect and tremendous potential to improve treatment of cancer. Target: Others. Smiles:...
Schlagworte: STING agonist-3 trihydrochloride (2138299-29-1 free base)
MW: 860.19 D
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Tat-NR2B9c acetate
Tat-NR2B9c acetate

Artikelnummer: TGM-T13112L1-10mg

Description: Tat-NR2B9c acetate (NA-1 acetate) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c acetate disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of...
Schlagworte: NA-1 acetate, Tat-NR2B9c acetate (500992-11-0 Free base)
MW: 2578.93 D
ab 48,00 €
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130 von 141 Seiten