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Dusquetide aceate
Artikelnummer: TGM-T13667L1-10mg
Description: Dusquetide aceate is an innate immune defense regulator against damage-associated molecular patterns and pathogen-associated molecular patterns. Dusquetide aceate shows anti-inflammation and antibacterial activities. Target: Antibacterial. Smiles:...
| Schlagworte: | Dusquetide aceate (931395-42-5 Free base) |
| MW: | 613.75 D |
ab 117,00 €
Selonsertib
Artikelnummer: SYN-1231-M100
Solid. Soluble in DMSO. Insoluble in water. Selonsertib, also known as GS-4997, is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. GS-4997 targets and binds to the catalytic kinase domain of ASK1 in an...
| Schlagworte: | GS-4997 (free base),... |
| Anwendung: | ASK1 inhibitor |
| CAS | 1448428-04-3 |
| MW: | 445,5 D |
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(2S,3R)-Voruciclib hydrochloride
Artikelnummer: TGM-T10096L2-50mg
Description: (2S,3R)-Voruciclib hydrochloride is the (2S,3R)-enantiomer of Voruciclib. It is an orally active CDK inhibitor. Target: Others. Smiles: Cl[H].ClC1=CC(C(F)(F)F)=CC=C1C(OC2=C(C(O)=CC(O)=C23)[C@H]([C@H]4CO)CCN4C)=CC3=O. References: Veena Agarwal, et al. A synergistic pharmaceutical combination for the...
| Schlagworte: | (2S,3R)-Voruciclib hydrochloride (1253731-24-6 free base) |
| MW: | 506.3 D |
ab 309,00 €
Casein Kinase II Inhibitor IV Hydrochloride
Artikelnummer: TGM-T10687L-100mg
Description: Casein Kinase II Inhibitor IV Hydrochloride is a small-molecule inducer of epidermal keratinocyte differentiation, offering novel therapeutic approaches for treating skin hyperproliferative disorders. Target: Others. Smiles: N#CCCC1=CC=CC(N2C=CC3=CN=C(NC4=CC(OC)=C(OC)C(OC)=C4)N=C32)=C1.Cl. References:...
| Schlagworte: | Casein Kinase II Inhibitor IV Hydrochloride (863598-09-8 free base) |
| Anwendung: | Casein Kinase II inhibitor |
| CAS | 2320347-54-2 |
| MW: | 465.93 D |
ab 1.520,00 €
Levofloxacin Hydrochloride Impurity A
Artikelnummer: TGM-T11007L-10mg
Description: Levofloxacin Hydrochloride Impurity A I, one of the quinolones, has a broad spectrum of antibacterial action. Target: Antibacterial. Smiles: O=C1C=2C3=C(C(=C(F)C2)N4CCNCC4)OC[C@H](C)N3C=C1C(O)=O.Cl. References: Ta O J , Yang J , Ma C , et al. Cellulose nanocrystals/graphene oxide composite for the...
| Schlagworte: | Levofloxacin Hydrochloride Impurity A(117707-40-1 Free base) |
| CAS | 2254176-11-7 |
| MW: | 397.83 D |
ab 88,00 €
Disitertide acetate
Artikelnummer: TGM-T11052L-10mg
Description: Disitertide acetate (P144 acetate) is a peptidic transforming growth factor-beta 1 (TGF-beta1) inhibitor specifically designed to block the interaction with its receptor. Disitertide acetate is also a PI3K inhibitor and an apoptosis inducer. Target: TGF-beta/Smad. Smiles:...
| Schlagworte: | P144 acetate, Disitertide acetate(272105-42-7 Free base) |
| MW: | 1640.88 D |
ab 150,00 €
Aldoxorubicin hydrochloride
Artikelnummer: TGM-T11090L1-10mg
Description: Aldoxorubicin hydrochloride is an albumin-binding prodrug of Doxorubicin, a DNA topoisomerase II inhibitor. Aldoxorubicin hydrochloride is released from albumin under acidic conditions. Aldoxorubicin hydrochloride exhibits potent antitumor activities in various cancer cell lines and in murine tumor...
| Schlagworte: | Aldoxorubicin hydrochloride (1361644-26-9 Free base) |
| CAS | 1361563-03-2 |
| MW: | 787.21 D |
ab 57,00 €
DREADD agonist 21 dihydrochloride
Artikelnummer: TGM-T11095-50mg
Description: DREADD agonist 21 dihydrochloride is a potent agonist of human muscarinic acetylcholine M3 receptors (hM3Dq) with an EC50 of 1.7 nM [1]. Target: Others. Smiles: Cl.Cl.C1CN(CCN1)C1=Nc2ccccc2Nc2ccccc12. References: Chen X, et al. The first structure-activity relationship studies for designer receptors...
| Schlagworte: | DREADD agonist 21 dihydrochloride (56296-18-5 free base) |
| CAS | 2250025-92-2 |
| MW: | 351.27 D |
ab 522,00 €
Duvelisib (R enantiomer) hydrochloride
Artikelnummer: TGM-T11129L-10mg
Description: Duvelisib (R enantiomer) hydrochloride (INK1197 R enantiomer HCl) is a PI3K inhibitor. Duvelisib (R enantiomer) hydrochloride is the less active enantiomer of Duvelisib. Target: PI3K. Smiles: C[C@H](C(N1C2=CC=CC=C2)=CC3=CC=CC(Cl)=C3C1=O)NC4=C5C(N=CN5)=NC=N4.Cl. References: Pingda Ren, et al. Certain...
| Schlagworte: | IPI-145 R enantiomer HCl, INK1197 R enantiomer HCl, Duvelisib (R enantiomer) hydrochloride(1261590-48-0 Free base) |
| MW: | 453.32 D |
ab 327,00 €
Camizestrant TFA
Artikelnummer: TGM-T11237L-10mg
Description: Camizestrant TFA (AZD-9833 TFA) is a potent and orally active antagonist of estrogen receptor (ER). Target: Estrogen Receptor/ERR. Smiles: FC(F)(F)CN1[C@H](C2=CC=C(C=N2)NC3CN(C3)CCCF)C4=C(C[C@H]1C)C5=C(NN=C5)C=C4.O=C(O)C(F)(F)F. References: Bernard Christophe Barlaam, etal. Chemical compounds. Patent...
| Schlagworte: | AZD-9833 TFA, Camizestrant TFA(2222844-89-3 Free base) |
| MW: | 590.54 D |
ab 98,00 €
gamma-secretase modulator 1 hydrochloride
Artikelnummer: TGM-T11358L-200mg
Description: Gamma-secretase inhibitor-1 is a gamma-secretase modulator valuable for Alzheimer's disease [1]. Target: Others. Smiles: CC1=CN(C2=CC=C(C=C2OC)NC3=NC4=C(S3)CCCC4C5=CC=CC=C5)C=N1.[H]Cl. References: Baumann, et al. Preparation of 4,5,6,7-tetrahydrobenzothiazolyl- or...
| Schlagworte: | gamma-secretase modulator 1 hydrochloride (1172637-87-4 free base) |
| CAS | 2741571-83-3 |
| MW: | 453 D |
ab 1.220,00 €
Chitinase-IN-2 hydrochloride
Artikelnummer: TGM-T10788L-100mg
Description: Chitinase-IN-2 hydrochloride functions as an inhibitor of both insect chitinase and N-acetyl hexosaminidase, and also serves as a pesticide. At concentrations of 50 µM and 20 µM, it demonstrates inhibitory effectiveness of 98% and 92% against chitinase and N-acetyl-hexosaminidase, respectively. Target:...
| Schlagworte: | Chitinase-IN-2 hydrochloride (1579991-63-1 free base) |
| CAS | 2070014-83-2 |
| MW: | 431.94 D |
ab 1.140,00 €