NOS Inhibitor Kit

This kit contains four nitric oxide synthase (NOS) inhibitors: 7-NI, L-NMMA, L-NIL, and L-NIO. 7-NI is a selective inhibitor for the brain nitric oxide synthase (NOS). Yellow orange solid soluble in DMSOStore desiccated at 4°CC7H5N3O2MW: 163.1[2942-42-9] L-NMMA (NG-Methyl-L-arginine, acetate salt) competitively inhibits nitric oxide synthase in a wide range of cells. White solid soluble in waterStore desiccated at 4°CC9H20N4O4MW: 248.3[53308-83-1] L-NIL (N6-(1-Iminoethyl)-lysine, hydrochloride) is a potent and selective inhibitor of nitric oxide synthase that exhibits about 28-fold greater selectivity for inducible nitric oxide synthase (IC50 = 3.3 uM) than for the rat brain constitutive enzyme (IC50 = 92 uM). It exhibits about 10-fold greater inhibitory potency than NG-monomethyl-L-arginine in inhibiting gamma-interferon-induced NO2?" production (IC50 = 460 nM). White solid soluble in waterStore at 4°CC8H19Cl2N3O2MW: 260.2[150403-89-7] L-NIO (N5-(1-Iminoethyl)-L-ornithine, dihydrochloride) is a potent, irreversible inhibitor of neutrophil nitric oxide synthase. White solid soluble in waterStore desiccated at -20°CC7H17Cl2N3O2MW: 246.1[36889-13-1]