TNF beta, Mouse

Sequence: LSGVRFSAAR TAHPLPQKHL THGILKPAAH LVGYPSKQNS LLWRASTDRA FLRHGFSLSN NSLLIPTSGL YFVYSQVVFS GESCSPRAIP AHEVQLFSSQ YPFHVPLLSA QKSVYPGLQG PWVRSMYQGA VFLLSKGDQL STHTDGISHL HFSPSSVFFG with polyhistidine tag at the N-terminus Endotoxin level: <0.1 EU per 1 µg of the protein by the LAL method. Protein function: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo. [The UniProt Consortium]