TNF Beta

Tumor Necrosis Factor - Beta (TNF-beta), also known as lymphotoxin-alpha is a human recombinant protein that can be used in a variety of applications including cytotoxicity, cell proliferation assays, and apoptosis. This product is best used for inducing apoptosis to create a positive control. Protein function: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo. [The UniProt Consortium]