Mouse MFGE8 Protein, His Tag

Recombinant mouse MFGE8 protein with C-terminal 6×His tag. Mouse MFGE8(Ala23-Cys463) 6×His tag, Protein function: Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization. [The UniProt Consortium]