Mouse IL-23 alpha&IL-12 beta Protein

Recombinant Mouse IL-23 alpha&IL-12 beta Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Val22-Ala196(IL-23 alpha)&Met23-Ser335(IL-12 beta). Interleukin (IL)-12 and IL-23 belong to the IL-12 type family and are composite cytokines, consisting of the common beta subunit p40 and the specific cytokine alpha subunit p35 and p19, respectively. IL-12 signals via the IL-12Rbeta1·IL-12Rbeta2 receptor complex, and IL-23 uses also IL-12Rbeta1 but engages IL-23R as second receptor.