IL16 Protein (Trx Tag) (recombinant mouse)

Sequence: Ser1205-Ser1322. Fusion tag: N-Trx Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method Observed Molecular Mass: 33 kDa. Protein function: Interleukin 16, also known as lymphocyte chemoattractant factor (LCF), refers to the C-terminal peptide of Mouse pro-IL-16 or neuronal IL-16, which are nuclear and cytoplasmic PD2 domain containing proteins. The C-termini of these proteins are cleaved by Caspase-3, resulting in the release of secreted IL-16. Mature IL-16 has been shown to bind the cell surface receptor CD4 and function as an immunomodulatory cytokine. The C-terminal peptide of human and Mouse IL-16 share approximately 86% amino acid sequence identity. Protein function: Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. [The UniProt Consortium]