Cynomolgus IFN gamma/IFNG Protein

Recombinant Cynomolgus IFN gamma/IFNG Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln24-Gln165. IFN-gamma and one of its receptor subunits, IFNGR1, are translocated to the nucleus, together with STAT1alpha as one macromolecular complex, via the classical importin-dependent pathway.Put IFN-gamma and its receptor subunit, IFNGR1, in direct contact with the promoter region of IFN-gamma-activated genes with associated increased activity, thus suggesting a transcriptional/cotranscriptional role for IFN-gamma/IFNGR1 as well as a possible role in determining the specificity of IFN-gamma action.