Canine IL-33 Recombinant Protein

The Canine IL-33 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Canine IL-33 applications are for cell culture, ELISA standard, and Western Blot Control. Canine IL-33 yeast-derived recombinant protein can be purchased in multiple sizes. Canine IL-33 Specifications: (Molecular Weight: 17.8 kDa) (Amino Acid Sequence: SIQEYSASLS TYNDQSITFV FEDGSYEIYV EDLRKGQEKD KVLFRYYDSQ SPSHETGDDV DGQTLLVNLS PTKDKDFLLH ANNEEHSVEL QKCENQLPDQ AFFLLHRKSS ECVSFECKNN PGVFIGVKDN HLALIKVGDQ TKDSYIEKTI FKLS). For research use only. Made in the USA. Protein function: Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury. [The UniProt Consortium]