Visfatin

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
009-001-W40-0025 25 µg - -

6 - 10 Werktage*

420,00 €
 
Visfatin purity was determined to be greater than 90% as determined by reducing and non-reducing... mehr
Produktinformationen "Visfatin"
Visfatin purity was determined to be greater than 90% as determined by reducing and non-reducing SDS-pAGE. Protein function: Catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression. [The UniProt Consortium]
Schlagworte: PBEF, Nampt, NAMPT, Visfatin, NAmPRTase, EC=2.4.2.12, Pre-B cell-enhancing factor, Pre-B-cell colony-enhancing factor 1, Nicotinamide phosphoribosyltransferase
Hersteller: Rockland Immunochemicals
Hersteller-Nr: 009-001-W40-0025

Eigenschaften

Konjugat: No
Wirt: E.coli
Spezies-Reaktivität: human

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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