TH protein (His tag), recombinant mouse

Activity: Testing in progress Protein Construction: A DNA sequence encoding the Mouse TH protein (P24529) (Phe 34-Leu 301) was expressed with a N-His tag. Sequence: Phe 34-Leu 301. Fusion tag: N-His Endotoxin: Please contact us for more information. Apparent Molecular Mass: 32 kDa. Protein function: Tyrosine hydroxylase (TH) is a rate-limiting enzyme in catecholamine synthesis. Tyrosine hydroxylase activity is modulated by protein-protein interactions with enzymes in the same pathway or the tetrahydrobiopterin pathway, structural proteins considered Protein function: Catalyzes the conversion of L-tyrosine to L- dihydroxyphenylalanine (L-Dopa), the rate-limiting step in the biosynthesis of cathecolamines, dopamine, noradrenaline, and adrenaline. Uses tetrahydrobiopterin and molecular oxygen to convert tyrosine to L-Dopa. In addition to tyrosine, is able to catalyze the hydroxylation of phenylalanine and tryptophan with lower specificity. Positively regulates the regression of retinal hyaloid vessels during postnatal development(PubMed:30936473). [The UniProt Consortium]