TH Mouse

Source: Sf9, Baculovirus cells.Sterile Filtered colorless solution.Tyrosine 3-monooxygenase (Th), is a rate-limiting enzyme in catecholamine synthesis. Th utilizes tetrahydrobiopterin as well as molecular oxygen to convert tyrosine to DOPA. Th regulates dopamine (DA) neurotransmission at the biosynthesis and reuptake steps. Th takes a vital part in the physiology of adrenergic neurons. Furthermore, Th effects overexpression in lymphocytes on the differentiation as well as function of T helper cells.TH Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 507 amino acids (1-498a.a.) and having a molecular mass of 57.0kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa).  TH is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques. Protein function: Plays an important role in the physiology of adrenergic neurons (Probable). Positively regulates the regression of retinal hyaloid vessels during postnatal development (PubMed:30936473). [The UniProt Consortium]