T-cell surface glycoprotein CD1c (CD1C), partial, human, recombinant

Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 18-302aa. Protein Length: Extracellular Domain. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: NADASQEHVS FHVIQIFSFV NQSWARGQGS GWLDELQTHG WDSESGTIIF LHNWSKGNFS NEELSDLELL FRFYLFGLTR EIQDHASQDY SKYPFEVQVK AGCELHSGKS PEGFFQVAFN GLDLLSFQNT TWVPSPGCGS LAQSVCHLLN HQYEGVTETV YNLIRSTCPR FLLGLLDAGK MYVHRQVRPE AWLSSRPSLG SGQLLLVCHA SGFYPKPVWV TWMRNEQEQL GTKHGDILPN ADGTWYLQVI LEVASEEPAG LSCRVRHSSL GGQDIILYWG HHFSM. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week. Relevance: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. Reference: "Human CD1b and CD1c isoforms survey different intracellular compartments for the presentation of microbial lipid antigens."Briken V., Jackman R.M., Watts G.F.M., Rogers R.A., Porcelli S.A.J. Exp. Med. 192:281-288(2000) . Function: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.