Recombinant Mouse TLR3/CD283 Protein (His Tag) (RPES3549)

Mouse TLR3/CD283 Recombinant Protein (RPES3549) is a highly pure recombinant protein developed by Assay Genie for use in a range of applications Protein function: Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response. [The UniProt Consortium]