PD-L2 (CD273), Fc fusion (Human) HiP(TM)

Human secreted Programmed Death Ligand 2 (PDL2)-Fc fusion protein, also known as CD273, PDCDL1G2, and B7-DC, GenBank Accession No. NM_025239, a.a. 20-219, expressed in a HEK293 cell expression system. MW = 49. Protein function: Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. [The UniProt Consortium]