PD-L1 Protein (canine), mFc Tag

PD-L1 Protein (canine), mFc Tag
NEU
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-32-18515-50 50 µg - -

3 - 11 Werktage*

1.028,00 €
ABE-32-18515-100 100 µg - -

3 - 11 Werktage*

1.317,00 €
 
Description: Recombinant Canine PD-L1 protein with C-terminal mouse Fc tag Background: This gene... mehr
Produktinformationen "PD-L1 Protein (canine), mFc Tag"
Description: Recombinant Canine PD-L1 protein with C-terminal mouse Fc tag Background: This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. Molecular Characterization: mass of 51.2 kDa after removal of the signal peptide. Tag: C-Mouse Fc tag
Schlagworte: Programmed death ligand 1, Canine PD-L1 Protein, mFc Tag
Hersteller: Abeomics
Hersteller-Nr: 32-18515

Eigenschaften

Konjugat: No
Wirt: Human cells
Spezies-Reaktivität: dog
Reinheit: >95% (SDS-PAGE)
Format: Lyophilized

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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