Leukocyte immunoglobulin-like receptor subfamily B member 3 (Lilrb3), partial, mouse, recombinant

Organism: Mus musculus (Mouse). Source: Mammalian cell. Expression Region: 25-642aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: SLPKPILRVQ PDSVVSRRTK VTFLCEETIG ANEYRLYKDG KLYKTVTKNK QKPENKAEFS FSNVDLSNAG QYRCSYSTQY KSSGYSDLLE LVVTGHYWTP SLLAQASPVV TSGGYVTLQC ESWHNDHKFI LTVEGPQKLS WTQDSQYNYS TRKYHALFSV GPVTPNQRWI CRCYSYDRNR PYVWSPPSES VELLVSGNLQ KPTIKAEPGS VITSKRAMTI WCQGNLDAEV YFLHNEKSQK TQSTQTLQEP GNKGKFFIPS VTLQHAGQYR CYCYGSAGWS QPSDTLELVV TGIYEYYEPR LSVLPSPVVT AGGNMTLHCA SDFPYDKFIL TKEDKKFGNS LDTEHISSSG QYRALFIIGP TTPTHTGAFR CYGYYKNAPQ LWSVPSALQQ ILISGLSKKP SLLTHQGHIL DPGMTLTLQC FSDINYDRFA LHKVGGADIM QHSSQQTDTG FSVANFTLGY VSSSTGGQYR CYGAHNLSSE WSASSEPLDI LITGQLPLTP SLSVQPNHTV HSGETVSLLC WSMDSVDTFI LSKEGSAQQP LRLKSKSHDQ QSQAEFSMSA VTSHLSGTYR CYGAQDSSFY LLSSASAPVE LTVSGPIETS TPPPTMSMPL GGLHMYLK. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week. Relevance: May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM). Reference: Molecular cloning of a novel murine cell-surface glycoprotein homologous to killer cell inhibitory receptors.Hayami K., Fukuta D., Nishikawa Y., Yamashita Y., Inui M., Ohyama Y., Hikida M., Ohmori H., Takai T.J. Biol. Chem. 272:7320-7327(1997). Function: nan