Human CHRM2 Protein, hFc Tag

Recombinant Human CHRM2 Protein with C-terminal human Fc tag. CHRM2(Met1-Glu22) hFc(Glu99-Ala330), Protein function: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3), this then triggers calcium ion release into the cytosol. [The UniProt Consortium]