Cynomolgus CTLA-4/CD152 Protein

Recombinant Cynomolgus CTLA-4/CD152 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala37-Ser160. CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses.CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation - a phenomenon which is particularly notable in cancers. It acts as an "off" switch when bound to CD80 or CD86 on the surface of antigen-presenting cells.