Cadherin-1 (CDH1), partial (Active), recombinant Macaca fascicularis

Organism: Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey). Source: Mammalian cell. Expression Region: 155-708aa. Protein Length: Partial. Tag Info: C-terminal 10xHis-tagged. Target Protein Sequence: DWVIPPISCP ENEKGPFPKN LVQIKSNKDK EGKVFYSITG QGADTPPVGV FIIERETGWL KVTEPLDREN IATYTLFSHA VSSNGNAVED PMEILITVTD QNDNKPVFTQ EVFKGSVMEG ALPGTSVMEV TATDADDDVN TYNAAIAYSI LSQDPELPDK NMFTINKNTG VISVVTTGLD RESFPMYTLV VQAADLQGEG LSTTATAVIT VTDTNDNPPV FNPTTYKGQV PENQANFVIT TLKVTDADAP NTPAWEAVYT ILNDNDGQFV VTTNPVTNDG ILKTAKGLDF EAKQQYILHV AVTNVAPFEV SLTTSTATVT VDVLDVNEAP IFVPPEKRVE VSEDFGVGQE ITSYTAREPD TFMEQKITYR IWRDAANWLE INPDTGAIST RAELDREDVE HVKNSTYTAL IIATDNGSPV ATGTGTLLLI LSDVNDNAPI PESRNLFFCE RNPKPQVINI IDADLPPNTS PFTAELMHGA SANWTIEYND PTQESIILKP KIALEVGDYK INLKLMDNQK KDQVTTLEVS VCDCEGAAGI CKKAPLVEAG MQIP. Purity: Greater than 95% as determined by SDS-PAGE. Endotoxin: Less than 1.0 EU/ug as determined by LAL method. Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus CDH1 at 2 µg/mL can bind Anti-CDH1 recombinant antibody (CSB-RA005034MA2HU). The EC50 is 2.256-2.744 ng/mL. Form: Lyophilized powder. Buffer: Lyophilized from a 0.2 µm filtered PBS, 6% Trehalose, pH 7.4. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. Relevance: Cadherins are calcium-dependent cell adhesion proteins E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production. Reference: n/a. Function: nan