Suc-Leu-Leu-Val-Tyr-AMC

Description: Suc-Leu-Leu-Val-Tyr-AMC is a fluorescent substrate for the 20S proteasome, as well as other chymotrypsin-like proteases (20S-proteasome/chymotrypsin). Smiles: CC(C)C[C@H](NC(=O)CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)Nc1ccc2c(C)cc(=O)oc2c1. References: Roberta L. Debiasi, et al. Reovirus-Induced Apoptosis Is Preceded by Increased Cellular Calpain Activity and Is Blocked by Calpain Inhibitors. J Virol. 1999 Jan, 73(1): 695-701.