Nelipepimut-S

Description: Nelipepimut-S, as an immunogenic peptide from the HER2 protein, is highly expressed in breast cancer. Smiles: [C@H](CC1=CC=CC=C1)(C(N[C@@H](CC(C)C)C(O)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@H](CCCCN)N)=O)[C@H](CC)C)=O)=O)=O)CO)=O)CC(C)C)=O)C)=O. References: Schneble EJ, Berry JS, Trappey FA, Clifton GT, Ponniah S, Mittendorf E, Peoples GE. The HER2 peptide nelipepimut-S (E75) vaccine (NeuVaxTM) in breast cancer patients at risk for recurrence: correlation of immunologic data with clinical response. Immunotherapy. 2014,6(5):519-31. doi: 10.2217/imt.14.22. Review. PubMed PMID: 24896623.