HUMAN PBK Peptide Pool

Pool of 78 overlapping peptides derived from a peptide scan (15mers with 11 aa overlap) through Lymphokine-activated killer T-cell-originated protein kinase (UniProtKB - Q96KB5) for T cell assays. One unit allows the stimulation of 2,5 x 10^8 cells.You can find applications and references in our blog post: Esophagogastric adenocarcinoma: Tumor-associated antigens, immune responses and HLA-I Expression Protein function: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin- induced DNA damage. [The UniProt Consortium]