CYM 50769

CYM 50769 is a nonpeptide antagonist of neuropeptides B and W receptor 1 (NPBWR1). It inhibits neuropeptide W-induced activation of NPBWR1 (IC50 = 0.12 µM). CYM 50769 is selective for NPBWR1 over a panel of 30 G protein-coupled receptors (GPCRs), enzymes, transporters, and ion channels at 30 µM.Formal Name: 5-chloro-2-(9H-fluoren-9-yl)-4-(4-methoxyphenoxy)-3(2H)-pyridazinone. CAS Number: 1421365-63-0. Molecular Formula: C24H17ClN2O3. Formula Weight: 416.9. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. lambdamax: 269 nm. SMILES: O=C1C(OC2=CC=C(C=C2)OC)=C(C=NN1C3C4=C(C5=C3C=CC=C5)C=CC=C4)Cl. InChi Code: InChI=1S/C24H17ClN2O3/c1-29-15-10-12-16(13-11-15)30-23-21(25)14-26-27(24(23)28)22-19-8-4-2-6-17(19)18-7-3-5-9-20(18)22/h2-14,22H,1H3. InChi Key: QHVSQUYCVUHYKT-UHFFFAOYSA-N.