Ac-YVAD-CHO

Description: L 709049 is a biologically active compound that is a selective inhibitor of interleukin-1beta converting enzyme (Caspase-1). Caspase inhibitors interfere with the initiation of apoptosis and have multiple clinical applications. Smiles: [C@@H](NC([C@H](CC1=CC=C(O)C=C1)NC(C)=O)=O)(C(N[C@H](C(N[C@@H](CC(O)=O)C=O)=O)C)=O)C(C)C. References: Yang HH, Jun HK, Jung YJ, Choi BK. Enterococcus faecalis activates caspase-1 leading to increased interleukin-1 beta secretion in macrophages. J Endod. 2014 Oct,40(10):1587-92. doi: 10.1016/j.joen.2014.06.015. Epub 2014 Aug 12. PubMed PMID: 25127933.