VAC14 (Vector pENTR223.1, Accession No. BC007214)

Length: 1575 Sequence: atggccaaca tcctggtgat ccactgccag acaacagatg acctcatcca gctgacagcc atgtgctgga tgcgggagtt catccagctg gcgggccgcg tcatgctgcc ttactcctcc gggatcctga ctgctgtctt gccctgcttg gcctacgatg accgcaagaa aagcatcaaa gaagtggcca acgtgtgcaa ccagagcctg atgaagctgg tcacccccga ggacgacgag ctggatgagc tgagacctgg gcagaggcag gcagagccca cccctgacga tgccctgcca aagcaggagg gcacagccag tggaggtcca gatggttcct gtgactccag cttcagtagc ggcatcagtg tcttcactgc agccagcact gaaagagccc cagtgaccct tcacctcgac gggatcgtgc aggtcctaaa ctgccacctc agtgacacgg ccattgggat gatgaccagg attgcagttc tcaagtggct ctaccacctc tacatcaaaa ctcctcggaa gatgttccgg cacacggaca gcctctttcc catcctactg cagacgttat cggatgaatc ggatgaggtg atcctgaagg acctggaggt gctggcagaa atcgcttcct cccccgcagg ccagacggat gacccaggcc ccctcgatgg ccctgacctc caggccagcc actcagagct ccaggtgccc acccctggca gagccggcct actgaacacc tctggtacca aaggcttaga atgttctcct tcaactccca ccatgaattc ttacttttat aagttcatga tcaaccttct caagagattc agcagcgaac ggaagctcct ggaggtcaga ggccctttca tcatcaggca gctgtgcctc ctgctgaatg cggagaacat cttccactca atggcagaca tcctgctgcg ggaggaggac ctcaagttcg cctcgaccat ggtccacgcc ctcaacacca tcctgctgac ctccacagag ctcttccagc taaggaacca gctgaaggac ctgaagaccc tggagagcca gaacctgttc tgctgcctgt accgctcctg gtgccacaac ccagtcacca cggtgtccct ctgcttcctc acccagaact accggcacgc ctatgacctc atccagaagt ttggggacct ggaggtcacc gtggacttcc tcgcagaggt ggacaagctg gtgcagctga ttgagtgccc catcttcaca tatctgcgcc tgcagctgct ggacgtgaag aacaacccct acctgatcaa ggccctctac ggcctgctca tgctcctgcc gcagagcagc gccttccagc tgctctcgca ccggctccag tgcgtgccca accctgagct gctgcagacc gaagacagtc taaaggcagc ccccaagtcc cagaaagctg actcccctag catcgactac gcagagctgc tgcagcactt tgagaaggtc cagaacaagc acctggaagt gcggcaccag cggagcgggc gtggggacca cctggaccgg agggttgtcc Protein function: The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts as a positive activator of PIKfyve kinase activity. Also required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes. [The UniProt Consortium]