USP45 (Vector pENTR223.1, Accession No. BC005991)

Length: 870 Sequence: atgcgggtga aagatccaac taaagcttta cctgagaaag ccaaaagaag taaaaggcct actgtacctc atgatgaaga ctcttcagat gatattgctg taggtttaac ttgccaacat gtaagtcatg ctatcagcgt gaatcatgta aagagagcaa tagctgagaa tctgtggtca gtttgctcag aatgtttaga agaaagaaga ttctatgatg ggcagctagt acttacttct gatatttggt tgtgcctcaa gtgtggcttc cagggatgtg gtaaaaactc agaaagccaa cattcattga agcactttaa gagttccaga acagagcccc attgtattat aattaatctg agcacatgga ttatatggtg ttatgaatgt gatgaaaaat tatcaacgca ttgtaataag aaggttttgg ctcagatagt tgattttctc cagaaacatg cttctaaaac acaaacaagt gcattttcta gaatcatgaa actttgtgaa gaaaaatgtg aaacagatga aatacagaag ggaggaaaat gcagaaattt atctgtaaga ggaattacaa atttaggaaa tacttgcttt tttaatgcag tcatgcagaa cttggcacag acttatactc ttactgatct gatgaatgag atcaaagaaa gtagtacaaa actcaagatt tttccttcct cagactctca gctggaccca ttggtggtgg aactttcaag gcctggacca ctgacctcag ccttgttcct gtttcttcac agcatgaagg agactgaaaa aggaccactt tctcctaaag ttctttttaa tcagctttgt cagaagcggg tgcatctaca Protein function: Catalyzes the deubiquitination of SPDL1 (PubMed:30258100). Plays a role in the repair of UV-induced DNA damage via deubiquitination of ERCC1, promoting its recruitment to DNA damage sites (PubMed:25538220). May be involved in the maintenance of photoreceptor function (PubMed:30573563). May play a role in normal retinal development. Plays a role in cell migration (PubMed:30258100). [The UniProt Consortium]