ID1 (Vector pENTR223.1, Accession No. BC000613)

Length: 468 Sequence: atgaaagtcg ccagtggcag caccgccacc gccgccgcgg gccccagctg cgcgctgaag gccggcaaga cagcgagcgg tgcgggcgag gtggtgcgct gtctgtctga gcagagcgtg gccatctcgc gctgcgccgg gggcgccggg gcgcgcctgc ctgccctgct ggacgagcag caggtaaacg tgctgctcta cgacatgaac ggctgttact cacgcctcaa ggagctggtg cccaccctgc cccagaaccg caaggtgagc aaggtggaga ttctccagca cgtcatcgac tacatcaggg accttcagtt ggagctgaac tcggaatccg aagttggaac ccccgggggc cgagggctgc cggtccgggc tccgctcagc accctcaacg gcgagatcag cgccctgacg gccgaggcgg catgcgttcc tgcggacgat cgcatcttgt Protein function: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. [The UniProt Consortium]