EZ Cap(TM) EGFP mRNA (mo5U)

EZ Cap(TM) EGFP mRNA encodes for enhanced GFP (EGFP), a variant of A. victoria GFP that contains chromophore mutations that increase the sensitivity of the protein and displays excitation and emission maxima of 489 and 511 nm, respectively. It is capped using a co-transcriptional capping method, resulting in the naturally occurring Cap 1 structure with high capping efficiency. EZ Cap(TM) EGFP mRNA is also polyadenylated and modified with 5-methoxy-UTP (mo5U) to inhibit RNA-mediated innate immune activation. Encapsulation of EZ Cap(TM) EGFP mRNA (mo5U) in lipid nanoparticles (LNPs) can be used for mRNA delivery and expression of EGFP in vitro or in vivo.Synonyms: EZ Cap(TM) EGFP mRNA (5-moUTP). Emission: 511 nm. Excitation: 489 nm. Formulation: (Request formulation change), 1 mM Sodium citrate, pH 6.4.