Voriconazole-d3 N-oxide

Voriconazole-d3 N-oxide is intended for use as an internal standard for the quantification of voriconazole N-oxide (Cay-28047) by GC- or LC-MS. Voriconazole N-oxide is a major metabolite of the triazole antifungal voriconazole (Cay-15633). It is formed via oxidation of voriconazole by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C19.Formal Name: (alphaR,betaS)-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol-d3, 1-oxide. CAS Number: 1217851-84-7. Molecular Formula: C16H11D3F3N5O2. Formula Weight: 368.3. Purity: >99% deuterated forms (d1-d3). Formulation: (Request formulation change), A solution in ethanol. Solubility: Ethanol: Slightly soluble: 0.1-1 mg/ml, Methanol: Slightly soluble: 0.1-1 mg/ml. SMILES: [2H]C([2H])([2H])[C@@H](C(C(F)=C1)=NC=N1=O)[C@@](O)(C2=C(C=C(C=C2)F)F)CN3C=NC=N3. InChi Code: InChI=1S/C16H14F3N5O2/c1-10(15-14(19)5-24(26)9-21-15)16(25,6-23-8-20-7-22-23)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3/t10-,16+/m0/s1/i1D3. InChi Key: KPLFPLUCFPRUHU-QLWAGJNOSA-N.