Midodrine-d6 (hydrochloride)

Midodrine-d6 is intended for use as an internal standard for the quantification of midodrine (Cay-17349) by GC- or LC-MS. Midodrine is a prodrug form of the alpha1-adrenergic receptor (alpha1-AR) agonist desglymidodrine. It is converted to desglymidodrine by enzymatic hydrolysis. Midodrine (5 mg/kg) increases mean arterial pressure (MAP) and decreases heart rate in normotensive rats. Formulations containing midodrine have been used in the treatment of orthostatic hypotension.Formal Name: 2-amino-N-[2-[2,5-di(methoxy-d3)phenyl]-2-hydroxyethyl]-acetamide, monohydrochloride. CAS Number: 1188265-43-1. Molecular Formula: C12H12D6N2O4 . HCl. Formula Weight: 296.8. Purity: >99% deuterated forms (d1-d6). Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble, Methanol: soluble. SMILES: NCC(NCC(C1=C(C=CC(OC([2H])([2H])[2H])=C1)OC([2H])([2H])[2H])O)=O.Cl. InChi Code: InChI=1S/C12H18N2O4.ClH/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13,/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16),1H/i1D3,2D3,. InChi Key: MGCQZNBCJBRZDT-TXHXQZCNSA-N.