Levobupivacaine-d9 (hydrochloride)

Levobupivacaine-d9 (hydrochloride)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay38904-1 1 mg -

6 - 10 Werktage*

82,00 €
Cay38904-5 5 mg -

6 - 10 Werktage*

383,00 €
Cay38904-10 10 mg -

6 - 10 Werktage*

726,00 €
 
Levobupivacaine-d9 is intended for use as an internal standard for the quantification of... mehr
Produktinformationen "Levobupivacaine-d9 (hydrochloride)"
Levobupivacaine-d9 is intended for use as an internal standard for the quantification of levobupivacaine (Cay-31596) by GC- or LC-MS. Levobupivacaine is a sodium channel blocker and local anesthetic, as well as the levorotary stereoisomer of bupivacaine (Cay-16618). It inhibits cardiac sodium channel currents (INa) by 57.8% in isolated guinea pig ventricular myocytes when used at a concentration of 10 µM. Levobupivacaine (10 µM) reduces the maximal rate of depolarization (Vmax) and action potential duration to 76.7 and 83.4% of controls, respectively, in isolated guinea pig papillary muscle. It induces a complete block of proprioception, motor function, and nociception in the hindleg of rats when administered at a dose of 7.7 mM by percutaneous injection into the sciatic nerve.Formal Name: 1-butyl-d9-N-(2,6-dimethylphenyl)-(2S)-2-piperidinecarboxamide, monohydrochloride. Synonyms: (S)-(-)-Bupivacaine-d9. Molecular Formula: C18H19D9N2O . HCl. Formula Weight: 333.9. Purity: >99% deuterated forms (d1-d9). Formulation: (Request formulation change), A solid. Solubility: DMF: 1 mg/ml, DMSO: 1 mg/ml. SMILES: CC(C=CC=C1C)=C1NC([C@H]2N(CCCC2)C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O.Cl. InChi Code: InChI=1S/C18H28N2O.ClH/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3,/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21),1H/t16-,/m0./s1/i1D3,4D2,5D2,12D2,. InChi Key: SIEYLFHKZGLBNX-KPHNNJCMSA-N.
Schlagworte: (S)-(-)-Bupivacaine-d9, 1-butyl-d9-N-(2,6-dimethylphenyl)-(2S)-2-piperidinecarboxamide, monohydrochloride
Hersteller: Cayman Chemical
Hersteller-Nr: 38904

Eigenschaften

Anwendung: GC-MS, LC-MS internal standard, quantification, sodium channel blocker, local anesthetic
MW: 333.9 D
Formel: C18H19D9N2O . HCl
Reinheit: >99% deuterated forms (d1-d9)
Format: Solid

Datenbank Information

KEGG ID : K04834 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Warning
GHS-Piktogramme:
H-Sätze: H315, H319, H335
P-Sätze: P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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