6alpha-hydroxy Paclitaxel-d5

An internal standard for the quantification of 6alpha-hydroxy paclitaxel 6alpha-hydroxy Paclitaxel-d5 is intended for use as an internal standard for the quantification of 6alpha-hydroxy paclitaxel (Cay-10009027) by GC- or LC-MS. 6alpha-hydroxy Paclitaxel is a metabolite of the antimitotic and anticancer agent paclitaxel (Cay-10461). It is formed from paclitaxel by the cytochrome P450 (CYP) isoform CYP2C8.Formal Name: (alphaR,betaS)-beta-(benzoyl-2,3,4,5,6-d5-amino)-alpha-hydroxy-benzenepropanoic acid, (2aR,3S,4R,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-3,4,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester. CAS Number: 1315376-90-9. Synonyms: 6alpha-hydroxy Taxol-d5. Molecular Formula: C47H46D5NO15. Formula Weight: 874.9. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: Soluble, DMSO: Soluble, Methanol: Soluble. SMILES: C[C@]1(C([C@@H](C2=C(C)[C@@H](OC([C@H](O)[C@H](C3=CC=CC=C3)NC(C4=C([2H])C([2H])=C([2H])C([2H])=C4[2H])=O)=O)C[C@]5(O)C2(C)C)OC(C)=O)=O)[C@@]([C@@H]5OC(C6=CC=CC=C6)=O)([H])[C@@]([C@@]7([H])[C@@H](O)[C@@H]1O)(CO7)OC(C)=O. InChi Code: InChI=1S/C47H51NO15/c1-24-30(61-43(57)33(51)32(27-16-10-7-11-17-27)48-41(55)28-18-12-8-13-19-28)22-47(58)40(62-42(56)29-20-14-9-15-21-29)36-45(6,38(54)35(60-25(2)49)31(24)44(47,4)5)37(53)34(52)39-46(36,23-59-39)63-26(3)50/h7-21,30,32-37,39-40,51-53,58H,22-23H2,1-6H3,(H,48,55)/t30-,32-,33+,34-,35+,36-,37-,39+,40-,45-,46+,47+/m0/s1/i8D,12D,13D,18D,19D. InChi Key: NDCWHEDPSFRTDA-NZSUPHSRSA-N. Origin: Synthetic.