Thromboxane B2

Thromboxane B2 (TXB2) is a non-enzymatically derived, stable, inactive metabolite of TXA2, which is highly unstable. Serum levels of TXB2 positively correlate with platelet COX-1 activation. Urinary levels of TXB2 reflect intrarenal TXA2 synthesis, while its metabolites, 11-dehydro TXB2 (Cay-19500) and 2,3-dinor TXB2 (Cay-19510), reflect systemic TXA2 secretion.Formal Name: 9alpha,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid. CAS Number: 54397-85-2. Synonyms: TXB2. Molecular Formula: C20H34O6. Formula Weight: 370.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: >50 mg/ml, DMSO: >25 mg/ml, Ethanol: >100 mg/ml, Methyl Acetate: 10 mg/ml, PBS pH 7.2: >100 µg/ml. SMILES: O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)OC(O)C1. InChi Code: InChI=1S/C20H34O6/c1-2-3-6-9-15(21)12-13-18-16(17(22)14-20(25)26-18)10-7-4-5-8-11-19(23)24/h4,7,12-13,15-18,20-22,25H,2-3,5-6,8-11,14H2,1H3,(H,23,24)/b7-4-,13-12+/t15-,16-,17-,18+,20?/m0/s1. InChi Key: XNRNNGPBEPRNAR-JQBLCGNGSA-N.