Tauroursodeoxycholic Acid MaxSpec(R) Standard

Tauroursodeoxycholic acid (TUDCA) is a taurine-conjugated form of the secondary bile acid ursodeoxycholic acid (Cay-15121). TUDCA is found in small quantities in human bile but at a higher concentration in the bile of black bears. It demonstrates anti-apoptotic activity in rodent models of tauopathy, Huntington's disease, ischemic brain injury, and retinal disorders. TUDCA MaxSpec(R) standard is a quantitative grade standard of TUDCA (Cay-20277) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This TUDCA MaxSpec(R) standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.Formal Name: 2-[[(3alpha,5beta,7beta)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid. CAS Number: 14605-22-2. Synonyms: 3alpha,7beta-dihydroxy-5beta-cholanoyl Taurine, TUDCA, UR-906. Molecular Formula: C26H45NO6S. Formula Weight: 499.7. Purity: >95%. Formulation: (Request formulation change), A solution in methanol at 100 µg/ml. SMILES: C[C@H](CCC(NCCS(O)(=O)=O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C. InChi Code: InChI=1S/C26H45NO6S/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17+,18-,19-,20+,21+,22+,24+,25+,26-/m1/s1. InChi Key: BHTRKEVKTKCXOH-LBSADWJPSA-N.