Stearoyl-L-carnitine-d3 (chloride)

Stearoyl-L-carnitine-d3 (chloride) is intended for use as an internal standard for the quantification of stearoyl-L-carnitine (Cay-26556) by GC- or LC-MS. Stearoyl-L-carnitine is a naturally occurring long-chain acylcarnitine. It inhibits sodium-dependent [3H]carnitine uptake in human proximal convoluted tubular (HPCT) cells by 52% when used at a concentration of 500 µM. It also inhibits lecithin:cholesterol acyltransferase activity in rat, but not human, plasma when used at a concentration of 500 µM. Plasma levels of stearoyl-L-carnitine are decreased in patients with chronic fatigue syndrome and increased in patients with end-stage renal disease.Formal Name: (R)-3-carboxy-N,N-dimethyl-N-(methyl-d3)-2-(stearoyloxy)propan-1-aminium, monochloride. CAS Number: 2245711-27-5. Synonyms: CAR 18:0-d3, C18:0 Carnitine-d3, L-Carnitine octdecanoyl ester-d3, L-Carnitine stearoyl ester-d3, L-Octadecanoylcarnitine-d3, Octadecanoyl-L-carnitine-d3, L-Stearoylcarnitine-d3, R-Stearoyl carnitine-d3. Molecular Formula: C25H47D3NO4 . Cl. Formula Weight: 467.1. Purity: >99% deuterated forms (d1-d3). Formulation: (Request formulation change), A solid. Solubility: DMF: 20 mg/ml, DMSO: 14 mg/ml, Ethanol: 20 mg/ml. SMILES: OC(C[C@H](C[N+](C([2H])([2H])[2H])(C)C)OC(CCCCCCCCCCCCCCCCC)=O)=O.[Cl-]. InChi Code: InChI=1S/C25H49NO4.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-25(29)30-23(21-24(27)28)22-26(2,3)4,/h23H,5-22H2,1-4H3,1H/t23-,/m1./s1/i2D3,. InChi Key: YSVYWVPJJXVIFM-UORIVOMASA-N.