SM-102

SM-102 is an ionizable cationic amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Administration of luciferase mRNA in SM-102-containing LNPs induces hepatic luciferase expression in mice. Formulations containing SM-102 have been used in the development of LNPs for delivery of mRNA-based vaccines. Read our statement on SM-102 for research use onlyFormal Name: 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]-octanoic acid, 1-octylnonyl ester. CAS Number: 2089251-47-6. Synonyms: CAY10779, Lipid H, LNP-102. Molecular Formula: C44H87NO5. Formula Weight: 710.2. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Chloroform: 100 mg/ml, Ethanol: 100 mg/ml. SMILES: OCCN(CCCCCCCC(OC(CCCCCCCC)CCCCCCCC)=O)CCCCCC(OCCCCCCCCCCC)=O. InChi Code: InChI=1S/C44H87NO5/c1-4-7-10-13-16-17-18-24-32-41-49-43(47)35-29-25-31-38-45(39-40-46)37-30-23-19-22-28-36-44(48)50-42(33-26-20-14-11-8-5-2)34-27-21-15-12-9-6-3/h42,46H,4-41H2,1-3H3. InChi Key: BGNVBNJYBVCBJH-UHFFFAOYSA-N.