Prostaglandin F1alpha-d9

Prostaglandin F1alpha-d9 (PGF1alpha.-d9) contains nine deuterium atoms at the 17, 17', 18, 18', 19, 19', 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of PGF1alpha by GC- or LC-mass spectrometry. PGF1alpha is the putative metabolite of dihomo-gamma-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1alpha and PGF2alpha have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10-11 M. PGF1alpha binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2alpha. It is only half as active as PGF2alpha in inducing human respiratory smooth muscle contractions in vitro.Formal Name: 9alpha,11alpha,15S-trihydroxy-prost-13E-en-1-oic-17,17,18,18,19,19,20,20,20-d9 acid. CAS Number: 1542166-81-3. Synonyms: PGF1alpha-d9. Molecular Formula: C20H27D9O5. Formula Weight: 365.6. Purity: >99% deuterated forms (d1-d9). Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: O[C@@H]1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@@H](O)CC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])[C@H](O)C1. InChi Code: InChI=1S/C20H36O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-19,21-23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,18-,19+/m0/s1/i1D3,2D2,3D2,6D2. InChi Key: DZUXGQBLFALXCR-XNRKUTMYSA-N.