Prostaglandin E1 ethyl ester

Prostaglandin E1 (PGE1) is the theoretical cyclooxygenase metabolite of dihomo-gamma-linolenic acid. Its pharmacology includes vasodilation, hypotension, and anti-platelet activities. The IC50 value of PGE1 for the inhibition of ADP-induced human platelet aggregation is 40 nM. PGE1 is used to treat male erectile dysfunction and to maintain ductus arteriosus patency in infants. PGE1 ethyl ester is an esterified form of the free acid which may be more amenable for certain applications.Formal Name: 11alpha,15S-dihydroxy-9-oxo-prost-13E-en-1-oic acid, ethyl ester. CAS Number: 35900-16-4. Synonyms: Alprostadil ethyl ester, PGE1 ethyl ester. Molecular Formula: C22H38O5. Formula Weight: 382.5. Purity: >95%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 0.25 mg/ml. lambdamax: 288 nm. SMILES: O=C1[C@H](CCCCCCC(OCC)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1. InChi Code: InChI=1S/C22H38O5/c1-3-5-8-11-17(23)14-15-19-18(20(24)16-21(19)25)12-9-6-7-10-13-22(26)27-4-2/h14-15,17-19,21,23,25H,3-13,16H2,1-2H3/b15-14+/t17-,18+,19+,21+/m0/s1. InChi Key: LVDCZROIKIHUKJ-QZCLESEGSA-N.