Pentadecanoyl-L-carnitine (chloride)

Pentadecanoyl-L-carnitine is a cannabinoid (CB) receptor agonist (EC50s = 3.7 and 3.2 µM for CB1 and CB2 receptors, respectively, in a cAMP modulation assay). It is also an agonist at the serotonin (5-HT) receptor subtypes 5-HT1A and 5-HT1B (EC50s = 9.6 and 9.3 µM, respectively) and an antagonist at histamine H1 and H2 receptors (EC50s = 10.9 and 6.1 µM, respectively). Pentadecanoyl-L-carnitine inhibits T cell proliferation in an SAg primary human cell system and reduces chemokine (C-C) motif ligand 2 (CCL2) levels in an Mphg primary human cell system.Formal Name: (R)-3-carboxy-N,N,N-trimethyl-2-[(1-oxopentadecyl)oxy]-1-propanaminium, monochloride. CAS Number: 173686-57-2. Synonyms: CAR 15:0, C15:0 Carnitine, L-Carnitine pentadecanoyl ester, L-Pentadecanoylcarnitine. Molecular Formula: C22H44NO4 . Cl. Formula Weight: 422.0. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Slightly soluble. SMILES: O=C(C[C@H](C[N+](C)(C)C)OC(CCCCCCCCCCCCCC)=O)O.[Cl-]. InChi Code: InChI=1S/C22H43NO4.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-22(26)27-20(18-21(24)25)19-23(2,3)4,/h20H,5-19H2,1-4H3,1H/t20-,/m1./s1. InChi Key: VAUHJRCIRYKXSR-VEIFNGETSA-N.