Palmitoleic Acid

Palmitoleic acid is an omega-7 monounsaturated fatty acid that has been found in macadamia and sea buckthorn oils. It increases basal and insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) protein levels in 3T3-L1 adipocytes when used at a concentration of 200 µM. Ex vivo, palmitoleic acid (300 mg/kg per day) increases glucose uptake and aerobic and anaerobic glycolysis and reduces de novo fatty acid synthesis and activity of the lipogenic enzymes ATP citrate lyase (ACL) and glucose-6-phosphate dehydrogenase (G6PDH) in isolated murine adipocytes. Dietary administration of palmitoleic acid (300 mg/kg) reduces high-fat diet-induced insulin resistance and liver inflammation in mice.Formal Name: (9Z)-hexadecenoic acid. CAS Number: 373-49-9. Synonyms: C16:1(9Z), C16:1 n-7, FA 16:1, (9Z)-Hexadecenoic Acid, cis-Palmitoleic Acid. Molecular Formula: C16H30O2. Formula Weight: 254.4. Purity: >99%. Formulation: (Request formulation change), A neat oil. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 50 mg/ml. SMILES: CCCCCC/C=C\CCCCCCCC(=O)O. InChi Code: InChI=1S/C16H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h7-8H,2-6,9-15H2,1H3,(H,17,18)/b8-7-. InChi Key: SECPZKHBENQXJG-FPLPWBNLSA-N. Side Chain Carbon Sum: 16:1.