ML-148

ML-148 is an inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH) with an IC50 value of 56 nM. It demonstrates selectivity for 15-PGDH when profiled across a panel of related dehydrogenase or reductase enzymes.Formal Name: [1-(3-methylphenyl)-1H-benzimidazol-5-yl]-1-piperidinyl-methanone. CAS Number: 451496-96-1. Molecular Formula: C20H21N3O. Formula Weight: 319.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml, DMSO: 5 mg/ml, Ethanol: 10 mg/ml. lambdamax: 213, 242 nm. SMILES: O=C(C1=CC=C(N(C2=CC=CC(C)=C2)C=N3)C3=C1)N4CCCCC4. InChi Code: InChI=1S/C20H21N3O/c1-15-6-5-7-17(12-15)23-14-21-18-13-16(8-9-19(18)23)20(24)22-10-3-2-4-11-22/h5-9,12-14H,2-4,10-11H2,1H3. InChi Key: YQNOQZALLOQMPY-UHFFFAOYSA-N.