Loteprednol etabonate

Loteprednol etabonate is a glucocorticoid receptor agonist with an affinity 4.3 times that of dexamethasone (Cay-11015). It decreases wound healing time in mice and minimizes scarring of rabbit cornea wounds. Formulations containing loteprednol etabonate are used in the treatment of inflammatory eye conditions.Formal Name: (11beta,17alpha)-17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-androsta-1,4-diene-17-carboxylic acid, chloromethyl ester. CAS Number: 82034-46-6. Molecular Formula: C24H31ClO7. Formula Weight: 467.0. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS(pH 7.2) (1:1): 0.2 mg/ml. lambdamax: 245 nm. SMILES: O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(OC(OCC)=O)C(OCCl)=O)=C1. InChi Code: InChI=1S/C24H31ClO7/c1-4-30-21(29)32-24(20(28)31-13-25)10-8-17-16-6-5-14-11-15(26)7-9-22(14,2)19(16)18(27)12-23(17,24)3/h7,9,11,16-19,27H,4-6,8,10,12-13H2,1-3H3/t16-,17-,18-,19+,22-,23-,24-/m0/s1. InChi Key: DMKSVUSAATWOCU-HROMYWEYSA-N.