Fingolimod (hydrochloride)

Fingolimod (hydrochloride)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay10006292-50 50 mg -

6 - 10 Werktage*

85,00 €
Cay10006292-100 100 mg -

6 - 10 Werktage*

149,00 €
Cay10006292-250 250 mg -

6 - 10 Werktage*

289,00 €
Cay10006292-1 1 g -

6 - 10 Werktage*

653,00 €
 
Fingolimod is an immune modulator, a prodrug form of the sphingosine-1-phosphate (S1P) receptor... mehr
Produktinformationen "Fingolimod (hydrochloride)"
Fingolimod is an immune modulator, a prodrug form of the sphingosine-1-phosphate (S1P) receptor agonist FTY720 phosphate (Cay-10008639), and a derivative of myriocin (Cay-63150). It selectively inhibits calcium-dependent cytosolic phospholipase A2 (cPLA2) over calcium-independent PLA2 (iPLA2) and secretory PLA2 (sPLA2) (Type V) when used at a concentration of 800 pmol and inhibits S1P lyase when used at concentrations ranging from 0.3 to 30 µM. Fingolimod (1 mg/kg) decreases the number of circulating lymphocytes in mice. It increases skin allograft survival in rats when administered at doses ranging from 0.3 to 3 mg/kg. Fingolimod (0.3 mg/kg) prevents disease development in a rat model of experimental autoimmune encephalomyelitis (EAE) induced by immunization with an emulsion of bovine spinal cord in complete Freund's adjuvant. Formulations containing fingolimod have been used in the treatment of multiple sclerosis.Formal Name: 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol, hydrochloride. CAS Number: 162359-56-0. Synonyms: FTY720. Molecular Formula: C19H33NO2 . HCl. Formula Weight: 343.9. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 20 mg/ml, Ethanol:PBS (pH 7.2) (1:1): 0.2 mg/ml. SMILES: CCCCCCCCC1=CC=C(CCC(N)(CO)CO)C=C1.Cl. InChi Code: InChI=1S/C19H33NO2.ClH/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20,15-21)16-22,/h9-12,21-22H,2-8,13-16,20H2,1H3,1H. InChi Key: SWZTYAVBMYWFGS-UHFFFAOYSA-N.
Schlagworte: FTY720, 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol, hydrochloride
Hersteller: Cayman Chemical
Hersteller-Nr: 10006292

Eigenschaften

Anwendung: Immune Modulator
MW: 343.9 D
Formel: C19H33NO2 . HCl
Reinheit: >98%
Format: Crystalline Solid

Datenbank Information

CAS : 162359-56-0| Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Warning
GHS-Piktogramme:
H-Sätze: H315, H319, H335, H412
P-Sätze: P261, P264, P271, P273, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Fingolimod (hydrochloride)"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen