CP-LC-1073

Lipid CP-LC-1073 is an ionizable cationic amino lipid derived from homocysteine, a naturally occurring amino acid. This lipid has demonstrated an efficient delivery and high protein expression of different kinds of RNA (mRNA, cRNA and saRNA) in vivo. Moreover, using a typical LNP formulation (IL/Ch/DOPE/PEG: 50/38.5/10/1.5), it has shown to induce specific lung targeting much more efficiently that other commercial alternatives through IV injection, with no signs of toxicity.Molecular Formula: C59H113N3O8S3. Formula Weight: 1088.7. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Ethanol: Soluble: >10 mg/ml. SMILES: O=C(NCCN(C)C)C(CCSCCC(OCCCCCCCCCCCCCCCCCC)=O)NC(CCCCC(CCSCCC(OCCCCCCCC)=O)SCCC(OCCCCCCCC)=O)=O. InChi Code: InChI=1S/C59H113N3O8S3/c1-6-9-12-15-18-19-20-21-22-23-24-25-26-27-30-35-46-69-57(65)41-51-72-49-39-54(59(67)60-43-44-62(4)5)61-55(63)37-32-31-36-53(73-52-42-58(66)70-47-34-29-17-14-11-8-3)38-48-71-50-40-56(64)68-45-33-28-16-13-10-7-2/h53-54H,6-52H2,1-5H3,(H,60,67)(H,61,63). InChi Key: XJVFPRMVAOPJGA-UHFFFAOYSA-N.