Cholic Acid-d4

Cholic Acid-d4
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay20849-1 1 mg -

6 - 10 Werktage*

109,00 €
Cay20849-5 5 mg -

6 - 10 Werktage*

161,00 €
Cay20849-10 10 mg -

6 - 10 Werktage*

299,00 €
 
Cholic acid-d4 is intended for use as an internal standard for the quantification of cholic acid... mehr
Produktinformationen "Cholic Acid-d4"
Cholic acid-d4 is intended for use as an internal standard for the quantification of cholic acid (Cay-20250) by GC- or LC-MS. Cholic acid is a primary bile acid. It is formed from cholesterol via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and CYP27A1. Cholic acid is conjugated to glycine or taurine by bile acid-CoA:amino acid N-acyltransferase (BAAT) to produce glycocholic acid (GCA, Cay-20276) and taurocholic acid (TCA, Cay-16215), respectively, in the liver, and is transformed into the secondary bile acid deoxycholic acid (DCA, Cay-20756) by intestinal microbiota. It induces C. difficile colony formation in an agar dilution assay when used at a concentration of 0.1% w/v. Dietary administration of cholic acid (0.4% w/w) increases serum cholesterol levels, biliary phospholipid secretion, and fecal DCA levels in rats.Formal Name: (5beta)-3alpha,7alpha,12alpha-trihydroxy-cholan-24-oic-2,2,4,4-d4 acid. CAS Number: 116380-66-6. Synonyms: Cholalic Acid-d4, Cholalin-d4. Molecular Formula: C24H36D4O5. Formula Weight: 412.6. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml, DMSO: 20 mg/ml, Ethanol: 20 mg/ml. SMILES: O[C@@H]1C([2H])([2H])C[C@@]2(C)[C@@](C[C@@H](O)[C@]3([H])[C@]2([H])C[C@H](O)[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCC(O)=O)([H])C1([2H])[2H]. InChi Code: InChI=1S/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1/i8D2,10D2. InChi Key: BHQCQFFYRZLCQQ-YFEOEUIKSA-N.
Schlagworte: Cholalic Acid-d4, Cholalin-d4, (5beta)-3alpha,7alpha,12alpha-trihydroxy-cholan-24-oic-2,2,4,4-d4 acid
Hersteller: Cayman Chemical
Hersteller-Nr: 20849

Eigenschaften

Anwendung: GC-MS, LC-MS, internal standard, cholic acid quantification
MW: 412.6 D
Formel: C24H36D4O5
Reinheit: >95%
Format: Crystalline Solid

Datenbank Information

CAS : 116380-66-6| Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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