C10 Ceramide (d18:1/10:0)

C10 ceramide is an endogenous, bioactive sphingolipid produced by ceramide synthase. C10 ceramide inhibits growth of wild-type and MDR1 gene-transfected MDA435/LCC6 human breast cancer cells with IC50 values of 44.1 and 46 µM, respectively. It also inhibits the growth of J774 murine macrophages in a dose-dependent manner. [Matreya, LLC. Catalog No. 1333]Formal Name: N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-decanamide. CAS Number: 111122-57-7. Synonyms: Cer(d18:1/10:0), C10 Ceramide, Ceramide (d18:1/10:0), N-decanoyl-D-erythro-Sphingosine. Molecular Formula: C28H55NO3. Formula Weight: 453.7. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 0.50 mg/ml. SMILES: OC[C@H](NC(CCCCCCCCC)=O)[C@H](O)/C=C/CCCCCCCCCCCCC. InChi Code: InChI=1S/C28H55NO3/c1-3-5-7-9-11-12-13-14-15-16-18-19-21-23-27(31)26(25-30)29-28(32)24-22-20-17-10-8-6-4-2/h21,23,26-27,30-31H,3-20,22,24-25H2,1-2H3,(H,29,32)/b23-21+/t26-,27+/m0/s1. InChi Key: FDWVAQFAMZLCAX-NBNLIBPQSA-N.