Butyrolactone II

Butyrolactone II is a butenolide fungal metabolite that has been found in A. terreus. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH, Cay-14805) and ABTS (Cay-27317) free radicals (EC50s = 11.5 and 68.5 µM, respectively). It inhibits 5-lipoxygenase (5-LO, IC50 = 21.43 µg/ml) and alpha-glucosidase (IC50 = 0.126 mM).Formal Name: (2R)-2,5-dihydro-4-hydroxy-3-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-5-oxo-2-furancarboxylic acid, methyl ester. CAS Number: 87414-44-6. Molecular Formula: C19H16O7. Formula Weight: 356.3. Purity: >95%. Formulation: (Request formulation change), A solid. SMILES: O=C1C(O)=C(C2=CC=C(O)C=C2)[C@](CC3=CC=C(O)C=C3)(C(OC)=O)O1. InChi Code: InChI=1S/C19H16O7/c1-25-18(24)19(10-11-2-6-13(20)7-3-11)15(16(22)17(23)26-19)12-4-8-14(21)9-5-12/h2-9,20-22H,10H2,1H3/t19-/m1/s1. InChi Key: AEKPZNDJHWFONI-LJQANCHMSA-N. Origin: Fungus/Aspergillus terreus.